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Antipsychotics in the ER

2/8/2017

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Since the 1950's, antipsychotics have become effective treatment for positive and negative symptoms of psychosis. With the introduction of second generation antipsychotics there was some decrease in the extrapyramidal effects associated with these medications, however side effects, including potentially deadly, are still commonly seen in the ER. 
Antipsychotics bind and inhibit dopamine receptors, causing the varying effects of these medications. This is also the source of many of the adverse effects of the medications.     
  • Major adverse reactions of antipyschotics
  • QTc prolongation
  • Neuroleptic Malignant Syndrome
  • Movement Disorders

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Hyperthyroidism and Thyroid Storm

2/5/2017

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Idrose A. Hyperthyroidism. In: Tintinalli JE, Stapczynski J, Ma O, Yealy DM, Meckler GD, Cline DM. eds. Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e. New York, NY: McGraw-Hill; 2016.

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Hydrofluoric Acid Treatment

2/1/2017

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Burns of dilute hydrofluoric acid are difficult to distinguish from other chemical burns and can appear as minimally erythematous areas of skin without blistering. Over 12-24 hours, however, this can progress to severe burns and blistering, progressing to necrosis requiring debridement. Highly concentrated acids may present with severely reddened, swollen areas with blanched regions which rapidly progress to necrosis. Even burns without impressive physical appearance may cause severe pain due to nerve ending irritation. HF is unique in that it does not spontaneously dissociate from hydrogen ions, causing it to penetrate through the skin and cause deeper, even systemic damage and hypocalcemia and hypomagnesemia. 


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This site is independently owned and operated and not affiliated with the George Washington University, George Washington University Hospital, or Medical Faculty Associates. All information on this site is the opinion of the author alone and in no way should be seen to represent the views of the George Washington University, George Washington University Hospital, or Medical Faculty Associates. The information on this page is for personal use only and should not be see as medical advice or used directly for patient care. The author provides no guarantee of the accuracy of the information provided on this page. ​

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  • Clinical
    • Discharge Macros
    • Procedure Macros
    • Exam Macros
    • Pediatric Macros
    • Antibiogram
    • Follow Up
    • 2023 MDM
    • Heart Pathway
    • Jeromy's Macros
  • Education
    • EM Education
    • Critical Care
    • FOAM
  • Orientation
    • Dept Orientation
    • Cerner
    • Dragon
  • Links
    • Clinical Links
    • StatMacros
    • ICU Bootcamp
  • Private
    • MCS
    • GWU Contacts & Map